Codeine in oral therapeutic dosage does not usually exert key effects on the cardiovascular method.
The result of promethazine and/or codeine on afterwards growth and advancement in the new child is mysterious.
Even so, codeine needs to be administered only less than near supervision to individuals using a record of drug abuse or dependence
This rapid conversion ends in larger than anticipated serum morphine levels. Even at labeled dosage regiments, people who are ultra-quick metabolizers may possibly expertise overdose signs and symptoms like Excessive sleepiness, confusion, and shallow respiration.
This medication can dry up and thicken mucus in the lungs, rendering it harder to breathe and clear your lungs. To aid stop this influence, consume a lot of fluids Except if normally directed by your health practitioner.
Administration of codeine might be accompanied by histamine release and may be utilized with caution in atopic children.
When provided concomitantly with promethazine, the dose of barbiturates really should be reduced by a minimum of one particular-half, as well as dose of narcotics must be lessened by one particular-quarter to 1-fifty percent. Dosage needs to be individualized. Abnormal amounts of promethazine HCl relative into a narcotic might bring on restlessness and motor hyperactivity while in the affected person with soreness; these signs and symptoms commonly disappear with sufficient Charge of the suffering.
Postmarketing scenarios of respiratory despair, such as fatalities, are documented with utilization of promethazine hydrochloride in pediatric clients less than two a long time of age. An array of excess weight-centered doses of promethazine hydrochloride have resulted in respiratory melancholy in these people.
Take the medication to a medication consider-back again method. Test with the pharmacy or legislation enforcement to find a site.
In advance of applying this medication, Females of childbearing age ought to speak with their health practitioner(s) regarding the threats and Positive aspects. Notify your medical professional If you're Expecting or Believe you may be pregnant. All through pregnancy, this medication is not really advisable. It may well a bit boost the hazard of birth defects if employed throughout the to start with two months of pregnancy. Also, utilizing it for a very long time or in significant doses close to the envisioned delivery date may possibly damage the unborn toddler.
Ensure you know how to acquire this product and what other medicine it is best to avoid getting with it. See also Drug Interactions portion. Get professional medical Promethazine codeine syrup enable instantly if any of these very really serious Uncomfortable side effects manifest: sluggish/shallow respiration, uncommon lightheadedness, severe drowsiness/dizziness, issue waking up.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people under six decades of age, since The mixture could lead to fatal respiratory depression During this age population. It's important that Promethazine Hydrochloride and Codeine Phosphate Syrup is calculated having an exact measuring device (see PRECAUTIONS- Information for Clients).
In case you are prescribed this medication on an everyday schedule and miss a dose, consider it the moment you recall. Whether it is close to the time of the following dose, skip the skipped dose. Get your future dose for the common time. Tend not to double the dose to capture up.
Codeine is improved into a strong opioid drug (morphine) in Your entire body. In some people, this change takes place a lot quicker and a lot more entirely than common, which raises the possibility of very critical Negative effects.